What is Spice? – Flavor Dance with Plants’ Chemical Weapons
- Devrim Karagoz
- May 1
- 10 min read

Although spice is often defined in everyday culinary language as simply a "flavoring" substance, scientifically and historically it encompasses a much broader concept.
In its simplest definition, spices are the parts of plants that contain aromatic components, such as roots, stems, seeds, fruits, barks, resins or flowers, usually dried and used. In this respect, they differ from herbs such as thyme or basil, which are used fresh in leaf form, because spices have more concentrated aromas and are often not consumed fresh, but are stored and used by drying.
The reason why spices are so effective is because plants develop defense systems against nature. The aromatic molecules found in most spices — terpenes, phenols, aldehydes, sulfur compounds, and the like — are actually chemical compounds produced by plants to protect themselves from insects , fight fungi , or deter animals . In short: while a plant defends itself, it also offers us humans an extraordinary treasure trove of flavors to use in the kitchen.
Throughout history, these powerful aromas have had medicinal , ceremonial and culinary functions. In ancient Egypt, cinnamon was used in mummification, while in medieval Europe, black pepper had a trade value rivaling gold. From the Indian Ayurvedic tradition to Chinese medicine, spices have appealed not only to the palate but also to the body’s balance.
Spices are both a plant’s self-protection strategy and a delicious coincidence of human history. These substances, which are the magic touch of the kitchen for us, are chemical weapons in nature. That’s why when you open a spice jar, you release not just a scent but also a biological story that goes back thousands of years.

Aromatic Components of Spices: Molecular Architects of Flavor
The smell or taste of a spice is not “accidentally pleasant” but is the result of delicate interactions between specific chemical compounds in the nose and palate.
The strong aromas of spices come from volatile aromatic compounds that they contain. These compounds are mostly oil-based and are stored in microscopic oil sacs of the spice. When the spice is crushed, roasted or heated, these sacs open and the aroma molecules are released.
These molecules interact not only with our sense of smell, but also with the nerve cells in our mouth, creating multi-layered perceptions such as sweetness, pungency, freshness or sharpness . The interesting thing is: most of these molecules are chemical agents produced by plants for defense or reproduction purposes . However, we humans perceive these signals as “taste”, not “danger”.
Some prominent groups of aromatic compounds are:
Phenols: Produce warm and sweet aromas. For example, eugenol is the dominant compound in cloves and provides a sweet-woody sensation as well as an antiseptic effect.
Terpenes: Create volatile notes such as pine, citrus, mint. There are varieties such as limonene , pinene , cineole . They are found in cardamom, fennel and thyme.
Aldehydes: Provide fruity and fresh aromas. For example, nonanal is found in sumac and hexanal is found in green coriander.
Sulfur compounds: Found in garlic, onion, and mustard; produce meaty, pungent flavors. Compounds such as allyl disulfide carry this character.
Pungent compounds: They produce sensation, not taste. Capsaicin in hot peppers and piperine in black pepper are in this group. They create a burning sensation on the tongue, but are not truly “bitter.”
Thanks to these compounds, a spice creates not only an aroma, but also a sensation : the warm bite of ginger, the freshness of mint, the long-lasting effect of cloves are all related to these molecules.

The Chemistry of Spices: Plant Defense, Our Taste
Behind the fascinating aromas carried by spices lies one of nature’s most impressive strategies: chemical defense . Plants cannot move; therefore, in order to survive, they fight their enemies with chemical weapons, not physical ones. The arsenal of this war consists of volatile aromatic compounds that we consider “flavors” in the kitchen.
So how do plants use these chemicals?
Plants usually store these compounds in oil glands or secretory sacs . Normally, these substances remain locked away in the plant's tissue. But when a threat—such as an insect bite, an animal grazing, or a fungal infection—occurs, the plant tissue is damaged and these sacs burst, releasing chemical defenses.
These substances act through the following mechanisms:
Taste deterrent: Many spice compounds are bitter, astringent, pungent, or burning. Animals find these tastes unpleasant and will stop eating the plant. ( Example: Capsaicin in hot peppers is stomach upsetting to animals but ineffective for birds - which allows the plant to spread seeds only through birds.)
Antimicrobial and antifungal: Many compounds in spices have antimicrobial properties. Eugenol (clove) and allicin (garlic) protect plant tissue from pathogens.
Communication and warning: Some plants “warn” other plants around them by releasing volatile compounds when they are under attack. This way, neighboring plants start producing defensive compounds in advance. This chemical communication acts as a kind of “early warning system” between plants.
( Example: Caryophyllene in cinnamon carries a danger signal to other cinnamon trees.)
Attract or repel pollinators: Aromatic floral spices (e.g. cloves) both attract pollinators with their pleasant scent and repel unwanted insects. They have a dual effect: selective attraction and active defense.
The human nose and tongue are evolutionarily programmed to perceive these chemicals as taste and aroma rather than danger . For example, piperine (the pungency of black pepper), which is a deterrent to animals, becomes the “accent” of spicy food in the human kitchen.
In short: Spices are the product of a flawless biological strategy developed by plants in their struggle to survive. These compounds, which are creative ingredients for us in the kitchen, are chemical weapons in nature. Thanks to this defense system, plants survive and we admire their intelligence at our table.

How to Detect Taste in Spices?
The impressive power of spices lies not only in taste, but in a complex collaboration of the senses. Feeling a spice on the tip of the tongue, smelling it behind the nose, and feeling its sting in the throat… This multi-dimensional experience is actually the result of the collaboration of three main systems:
1. Taste (Gustatory System)
The taste buds on our tongues can only detect five basic tastes: sweet, salty, sour, bitter, and umami . Most spices don’t directly impart these flavors. For example, black pepper or ginger aren’t “hot” — because the bitterness is detected by pain receptors, not taste buds.
2. Smell (Olfactory System)
This is where the real power of spices lies. Volatile compounds evaporate during cooking or chewing and reach the nasal cavity. There, they are recognized by olfactory receptors and transmitted to the brain as “aroma.” This is why food tastes unpleasant when the nose is blocked — because the aroma, not the taste, is not detected.
3. Trigeminal System (Sense of Feeling)
Some spices create physical sensations: compounds like piperine in black pepper, capsaicin in cayenne pepper, and allyl isothiocyanate in mustard can cause pain, heat, tingling, or coolness . If your tongue burns, it’s not “taste,” but a neural response to the perception of danger . The biting heat of ginger and the coolness of mint are all related to this system.
Spices are not just a taste bud, they are a sensory symphony that acts on the nose, tongue and nervous system at the same time. So using good spices does more than just add flavour: they give the dish a character, a soul, a physical sensation.
Spices' Response to Heat: Flavor's Fate Is Written in the Pot
Spices make a difference not only in what they are, but also in when and how they are used . Because the aromatic compounds they contain are very sensitive to heat. Adding a spice at the wrong time can cause it to lose all its potential. On the other hand, the right heat treatment brings out the true character of that spice.
1. Volatility and Vanishing Aromas
Most of the spice aromas are made up of volatile oils . These compounds can evaporate quickly, especially at high temperatures.
Fresh, floral, citrusy flavors like terpenes (e.g. coriander, fennel, cardamom) cannot withstand long cooking . Such spices should generally be added towards the end of the dish or just before serving.
Phenols and some sulfur compounds (such as cloves, garlic, cumin) are more resistant and can remain aromatic even during long cooking times.
2. Deepening the Flavor by Roasting
Some spices deepen their flavor by toasting them in a dry pan or gently heating them in oil. This process opens the oil sacs inside them and “carries” the flavor of the spice into the food.
Example: Cumin, coriander and fennel seeds gain toasty, nutty notes when lightly tossed in a pan.
In Indian cuisine , this technique is known as “tempering”: mustard seeds, fennel and garlic are thrown into the oil and within seconds, all the aroma is released into the oil.
3. Powder or Grain?
While powdered spices release aroma more quickly because they have a larger surface area, they also go stale just as quickly.
Whole spices (e.g. black pepper, coriander, cardamom) release aroma as soon as they are ground, and the most intense effect is achieved with freshness .
Suggestion: The act of “adding spices to food” actually means managing chemical reactions . Whoever controls the aroma in the triangle of heat, oil and time determines the fate of the food.

Chemical Harmony in Spice Mixtures: Flavor Begins with Balance
Using spices individually is great, but the real magic happens in harmonious combinations . But there’s an important distinction here: throwing every powerful spice into the same pot doesn’t necessarily create a rich flavor. On the contrary, some spices clash , while others complement each other by sharing the same aromatic foundation. This is where “spice chemistry” comes into play.
1. Common Aromatic Compounds = Harmony
If spices are similar in certain aromatic compounds, they usually create a harmonious and balanced flavor profile when combined. For example:
Eugenol- bearing cloves, cinnamon and nutmeg create a warm and sweet depth together.
Cardamom, black pepper and bay leaf containing cineole create a refreshing, rejuvenating synergy.
This approach also explains the classic blends that chefs intuitively create: → Indian garam masala, → the Middle Eastern spice za'atar, → North African ras el hanout.
2. Creating an Aroma Bridge
Sometimes two spices are not directly compatible, but a connection can be made by adding a “bridge spice”. Example:
Anise (anethole) and coriander (linalool) have different structures, but cinnamon (eugenol) can form an aromatic bond with both of them, creating a flavor bridge .
With this method, the spice blend becomes a more balanced , multi-dimensional experience that offers a different layer of aroma with each sip.
3. Yin-Yang: Balance with Opposite Tastes
Spice harmony is not just about similarity, it is also about balance :
Sweetish clove + acidic sumac
Hot black pepper + cooling coriander
Woody cumin + citrusy lemongrass
In masterful mixtures there is always a “balancing element”.

What Change Does Spice Knowledge Make in the Kitchen?
Knowing spices is not just about “knowing what goes with what.” This knowledge makes it possible to make creative decisions in the kitchen. Because each spice exhibits different behaviors, not only in terms of aroma, but also in terms of heat, oil, other compounds, and time . Knowing these transforms cooking from a recipe memorization to an art based on creativity .
1. From Memorization of Recipes to Conscious Decisions
When you know how to use spices, you’re no longer stuck with a recipe’s “1 teaspoon cumin” recommendation. It’s your choice in what form (powder, roasted, fresh?) and at what stage (at the beginning, in oil, or at the end?) to add the cumin.
Bottom line: You control the food , not the recipe.
2. Ability to Create New Mixtures
A culinary understanding supported by scientific knowledge will allow you to create not only traditional spice blends but also personal flavor signatures . A chef who knows common flavor components, balance points and taste-sense relationships will not be dependent on recipe books.
3. Creative Harmonies, Intercultural Tastes
It is possible to combine spices that are said to be “unsuitable” for a dish with scientific pairing. Example:
The combination of cinnamon + orange peel + coriander seed, which is unusual in Turkish cuisine, can give excellent results in both desserts and meat dishes.
4. Maximum Effect with Minimum Spice
Spice knowledge guides you to the right 3 types , not 10. When you know the power of each spice, you make the right choices, not too many. This means economical, simple and powerful recipes.
Science-Backed Spice Tips
For more aroma, more balance, more impact in your kitchen...
1. Dissolve in oil, release aroma: Most spices are oil-soluble. To enhance aroma, sauté the spices in a little oil first.
2. Volatile aromas = towards the end of cooking: Add spices with citrus, floral or fresh notes (e.g. coriander, cardamom) at the end of cooking.
3. Granular spices are strong when fresh: Use spices like black pepper and cardamom immediately after they are ground; the aroma fades quickly.
4. Create layers by roasting: Dry-roasting spices adds nutty and earthy notes.
5. Bitterness is transferred to oil, acid to water: While hot peppers are transferred better to oil, acidic spices like sumac are transferred better to water-based dishes.
6. Spices go well with desserts too: Spices such as cinnamon, saffron, and mahaleb add character to fruit and milk desserts.
7. Spice + Acidity + Oil = Flavor triangle: Oil carries the flavor, acidity (lemon, vinegar) creates balance. All three together are the basis of flavor.
8. Less is more: The right spice is important, not too much spice. You can create deep flavors with a few harmonious spices.

Conclusion: Spice is a Science as Well as an Art
To see spices as merely “flavor enhancers” would be to underestimate them. In fact, each spice is both a plant’s defense strategy , a sensory explosion , and a cultural memory of human history . Thousands of years of trade routes, recipes, traditions, and modern molecular gastronomy knowledge have been shaped around these small but effective ingredients.
As we have seen in this article, the effect of a spice is not just about what it is, but how the molecules in it behave :
Does it contain essential oils?
Is it heat resistant?
Does it give taste or does it create sensation?
What aromatic bonds does it form with other spices?
All these questions transform spices from being a "culinary element" into a scientific and artistic tool . Just as a composer plays with notes, a conscious cook plays with spices: establishing balance, creating contrast, emphasis or creating a background to bring the main ingredient to the forefront.
And the best part is: this knowledge is not the exclusive preserve of professional chefs. This intuitive approach combined with science can be developed in every home kitchen.
You can bring the warmth of the earth to your plate with a pinch of cumin, the freshness of the East with a pinch of cardamom, and the depth of the Mediterranean with a bay leaf. It is possible to tell stories, not to cook with spices.
Seasoning is truly both a science and an art, and where the two meet: your kitchen.
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